SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Neurorehabilitation and Neural Repair
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Weller, P.
Right arrow Articles by Seitz, R. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Weller, P.
Right arrow Articles by Seitz, R. J.
Right arrowPubmed/NCBI databases
Medline Plus Health Information
*Stroke
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Motor Recovery as Assessed with Isometric Finger Movements and Perfusion Magnetic Resonance Imaging after Acute Ischemic Stroke

Patrick Weller, MD

Department of Neurology, University Hospital Düsseldorf, Düsseldorf, Germany

Hans-Jörg Wittsack, PhD

Institute of Diagnostic Radiology, University Hospital Düsseldorf, Düsseldorf, Germany

Mario Siebler, MD

Department of Neurology, University Hospital Düsseldorf, Düsseldorf, Germany, Biomedical Research Center, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany

Volker Hömberg, MD

Neurological Therapy Center, Düsseldorf, Germany

Rüdiger J. Seitz, MD

Department of Neurology, University Hospital Düsseldorf, Düsseldorf, Germany, Biomedical Research Center, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany, Brain Imaging Center West, Research Center Jülich, Jülich, Germany, Seitz{at}neurologie.uni-duesseldorf.de

Objective. Recovery from hemiparetic stroke is variable. An important goal for clinicians and clinical researchers is to identify predictors of recovery. The initial phase after acute ischemic stroke is considered to be of major importance for neurological outcome. The authors sought to determine in patients with acute ischemic stroke whether early motor recovery, as measured by repetitive isometric index-thumb oppositions, is correlated with ischemic lesion volume. Methods. Thirty-six acute hemiparetic stroke patients with residual hand function were investigated. The European Stroke Scale (ESS) score was determined on admission and at discharge. Performance of repetitive index finger-thumb pinch movements was measured daily during the 1st 8 days after stroke onset. Brain ischemia volume was determined digitally in time-to-peak magnetic resonance images of per-fusion. Results. The recovery of patients with (P = 0.002) and without (P < 0.001) thrombolysis as assessed with the ESS was paralleled by an increase in isometric grip force and movement rate (P < 0.05). Recovery was predicted by the area of moderately impaired perfusion indicated by the per-fusion mismatch volume (r = 0.578, P < 0.001). Conclusions. In acute stroke, recovery of hand function is predicted by the volume of salvageable ischemic tissue, as determined by the perfusion mismatch.

Key Words: Stroke • Recovery • Movement kinetics • Perfusion mismatch

Neurorehabilitation and Neural Repair, Vol. 20, No. 3, 390-397 (2006)
DOI: 10.1177/1545968305285037


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
Neurorehabil Neural RepairHome page
H.-M. Chen, C. C. Chen, I-P. Hsueh, S.-L. Huang, and C.-L. Hsieh
Test-Retest Reproducibility and Smallest Real Difference of 5 Hand Function Tests in Patients With Stroke
Neurorehabil Neural Repair, June 1, 2009; 23(5): 435 - 440.
[Abstract] [PDF]


Home page
StrokeHome page
B. H. Dobkin
Behavioral, Temporal, and Spatial Targets for Cellular Transplants as Adjuncts to Rehabilitation for Stroke
Stroke, February 1, 2007; 38(2): 832 - 839.
[Abstract] [Full Text] [PDF]



Advertisement