|
Sign In to gain access to subscriptions and/or personal tools.
|
First published on March 8, 2008, doi:10.1177/1545968307313502
Neurorehabilitation and Neural Repair 2008;22:355.
A more recent version of this article appeared on July 1, 2008
Endurance and Resistance Exercise Training Programs Elicit Specific Effects on Sciatic Nerve Regeneration After Experimental Traumatic Lesion in Rats
Jocemar Ilha,
Rafaela T. Araujo,
Tais Malysz,
Erica E. S. Hermel,
Paula Rigon,
Leder L. Xavier,
and
Matilde Achaval*
* To whom correspondence should be addressed. E-mail: achaval{at}ufrgs.br.
 |
Abstract |
|---|
Objective. To evaluate the effects of endurance, resistance, and a combination of both types of exercise training on hindlimb motor function recovery and nerve regeneration after experimental sciatic nerve lesion in rats. Methods. Sciatic nerve crush was performed on adult male rats, and after 2 weeks of the nerve lesion, the animals were submitted to endurance, resistance, and a combination of endurance-resistance training programs for 5 weeks. Over the training period, functional recovery was monitored weekly using the Sciatic Functional Index (SFI) and histological and morphometric nerve analyses were used to assess the nerve regeneration at the end of the trainings. Results. The SFI values of the endurance-trained group reached the control values from the first posttraining week and were significantly better than both the resistance-trained group at the first, second, and third posttraining weeks and the concurrent training group at the first posttraining week. At the distal portion of the regenerating sciatic nerve, the endurance-trained group showed a greater degree of the myelinated fiber maturation than the sedentary, resistance-trained, and concurrent training groups. Furthermore, the endurance-trained group showed a smaller percentage area of endoneurial connective tissue and a greater
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati What's this?
|
