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Neurorehabilitation and Neural Repair
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Disease Characteristics and Psychological Status in Multiple Sclerosis

Nicholas G. LaRocca

Albert Einstein College of Medicine, Bronx, New York

Labe C. Scheinberg

Albert Einstein College of Medicine, Bronx, New York

Seymour R. Kaplan

Albert Einstein College of Medicine, Bronx, New York

A variety of psychological reactions have been observed in multiple sclerosis (MS), with depressive symptoms and alterations in self-concept among the most prominent. In a pilot study (n = 53) followed by two waves of a prospective study (n = 94, n = 66), structured interviews were used to examine the relationship between disease characteristics and psychological status in a sample of MS outpatients. Depressive symptoms were common but severe depressive illness was rare. Patients who were more neurologically impaired and more disabled in activities of daily living reported a more negative self-concept but did not report higher levels of depressive symptoms, demoralization, or negative affect balance. In contrast, patients reporting an exacerbation at the time of the interview tended to report a more negative self-concept, higher levels of demoralization, and a more negative affect-balance. The implications of these findings for psychological assessment and treatment are discussed.

Key Words: Multiple sclerosis • —Disease characteristics • —Psychological status.

Neurorehabilitation and Neural Repair, Vol. 1, No. 4, 171-178 (1987)
DOI: 10.1177/136140968700100404
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